OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-MAPK8 antibodies

Anti-MAPK8 Antibody EPR140(2)

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307854
  • Rabbit monoclonal antibody against JNK1(clone EPR140(2))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC408403) , 20ug
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)
spacer
Also for MAPK8 (NM_139049)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human JNK1 was used as an immunogen.
Clone NameEPR140(2) IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase 8 (MAPK8), transcript variant JNK1-a2
Alternative NameJNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1; SAPK1c
Database LinkNP_620637
FunctionC-Jun N-terminal kinase 1 (JNK1) is a member of the mitogen-activated protein kinase (MAPK) family (1). It is activated by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, such as AP-1, and thus regulates AP-1 transcriptional activity (2). JNK1 regulates microtubule assembly in neuronal cells and microtubule-associated proteins (MAP) activity, maintaining the cytoskeletal integrity of neurons (1). In T-cells, JNK1 and its JNK2 are required for polarized differentiation of T-helper cells into Th1 cells (2). JNK1 plays a role in obesity (3). A JNK1 deficiency results in reduced adiposity and improved insulin sensitivity (3).
Related Pathway
EGFR1 Signaling Pathway
Focal Adhesion
MAPK signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway
Wnt Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - JNK1 antibody [EPR140(2)]; All lanes : Anti-JNK1 antibody [EPR140(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : 293T cell lysate.Lane 3 : K562 cell lysate.Lane 4 : MCF7 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 48 kDa.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title