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Home Antibody All anti-MAPK6 antibodies

Anti-MAPK6 Antibody EP1720Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300927
  • Rabbit Monoclonal Antibody against MAPK6 (Clone EP1720Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400969) , 20ug
100ul $325 3-7 Days
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WB(1)
IHC(1)
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Also for MAPK6 (NM_002748)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminal of human ERK3 protein was used as an immunogen.
Clone NameEP1720Y IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsIP: Use at an assay dependent dilution; WB: 1:1000 - 1:10000; FC: 1:45; IHC-P: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC/IF.

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase 6 (MAPK6)
Alternative NameERK3; HsT17250; p97MAPK; PRKM6
Database LinkNP_002739
FunctionERK3 (Extracellular signal-regulated kinase 3, MAPK6, p97 MAPK) belongs to the Ser/Thr protein kinase family and is a member of the mitogen-activated protein (MAP) kinase superfamily. Unlike the other members of the MAPK family, ERK3 is a mitogen-activated protein kinase homologue that has SEG motif instead of conserved TXY motif in the activation loop (1). Also, unlike ERK1 and ERK2, it is ubiquitously expressed and localized in the nucleus of proliferating cells (2). Highly unstable, ERK3 is constitutively degraded during ubiquitin-proteasome pathway of proliferating cells (3). ERK3 has been linked to phosphorylation MAP2 and as a possible regulator during cell differentiation (4).
Related Pathway
Focal Adhesion
MAPK signaling pathway

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WB Image
Western blot - MAPK6 antibody [EP1720Y]; Anti-MAPK6 antibody [EP1720Y] at 1/1000 dilution + HeLa cell lysate at 10 µg.Secondary.Goat anti-Rabbit HRP labeled at 1/2000 dilution.Predicted band size : 63 kDa.Observed band size : 105 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - MAPK6 antibody [EP1720Y]; Ab53277 (1:50) staining human MAPK6 in human breast carcinoma tissue by immunohistochemistry using paraffin embedded tissue.

 

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