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Home Antibody All anti-MAPK3 antibodies

Anti-MAPK3 PHOSPHO Antibody EP197Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301085
  • Rabbit Monoclonal Antibody against MAPK3 (Clone EP197Y) (Phospho-specific)
100ul 325 3-7 Days
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WB(1)
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Also for MAPK3 (NM_002746)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA phospho specific peptide corresponding to residues surrounding Threonine 202 and 204 of human Erk1/p44. This antibody detects Erk1/p44 phosphorylated at Threonine 202 and 204.
Clone NameEP197Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:2000; IP: 1:20
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 1
Alternative NameERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM3
Database LinkNP_002737
Entrez Gene 5595 Human
Entrez Gene 26417 Mouse
Entrez Gene 50689 Rat
FunctionExtra cellular signal-regulated kinases Erk1 (p44 MAPK) Serine/Threonine protein kinase is part of a subfamily of mitogen-activated protein kinases that participate in diverse cellular functions, including the regulation of cell growth, differentiation, apoptosis and signal transduction (1,2,3). Erk1 regulates meiosis and mitosis by phosphorylating a number of transcription factors such as ELK-1. Activation of Erk1 occurs through phosphorylation of threonine 202 and tyrosine 204 (of human MAP kinase) . Erk1 is also known to autophosphorylate on tyrosine (4).
Related PathwayProtein KinaseES Cell Differentiation/IPSDruggable Genome MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwayOocyte meiosismTOR signaling pathwayVascular smooth muscle contractionMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-ERK1 (pY204) + ERK2 (pY187) antibody [EP197Y]; All lanes : Anti-ERK1 (pY204) + ERK2 (pY187) antibody [EP197Y] at 1/2000 dilution.Lane 1 : A431 cell lysate.Lane 2 : A431 cell lysate treated with EGF.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 43 kDa.Observed band size : 43 kDa.

 

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