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Anti-MAPK3 Antibody Y72
Also for MAPK3 (NM_002746)
|A synthetic peptide corresponding to residues near N-terminus of human ERK1 was used as immunogen. The antibody does not cross-react with other MAP kinases.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000; ICC: 1:100; IP: 1:40; FC: 1:40; IHC-P: Use at an assay dependent dilution; ICC/IF: 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Protein A purified
|Does not react with Rat
|Homo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 1|
|ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM3|
|p44 MAP Kinase (Erk1) is a member of a family of mitogen-activated protein kinases that participate in diverse cellular functions, including the regulation of cell growth and differentiation (1,2). Erk1 regulates meiosis and mitosis by phosphorylating a number of transcription factors such as ELK-1. Activation of Erk1 occurs through phosphorylation of threonine 202 and tyrosine 204 (of human MAP kinase) (3). Erk1 is also known to autophosphorylate on tyrosine (3).|
Delta-Notch Signaling Pathway
EGFR1 Signaling Pathway
MAPK signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway
Wnt Signaling Pathway
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Western blot - ERK1 antibody [Y72]; Anti-ERK1 antibody [Y72] at 1/1000 dilution + Jurkat cell lysate.Predicted band size : 43 kDa.Observed band size : 43 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ERK1 antibody [Y72]; TA300312 staining ERK1 in lung carcinoma by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).