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Anti-MAPK3 Antibody Y73

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

WB(1)

OriGene Data

Immunogen	A synthetic peptide corresponding to residues human Erk1 was used as immunogen. The antibody can detect Erk1 and Erk1b.
Clone Name	Y73	Isotype	IgG
Species Reactivity	Human, Mouse, Rat	Concentration
Guaranteed Application *	WB	Suggested Dilutions	WB: 1: 1,000
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 1
Alternative Name	ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM3
Database Link	NP_002737
Function	p44 MAP Kinase (Erk1) is a member of a family of mitogen-activated protein kinases that participate in diverse cellular functions, including the regulation of cell growth and differentiation (1,2). Erk1 regulates meiosis and mitosis by phosphorylating a number of transcription factors such as ELK-1. Activation of Erk1 occurs through phosphorylation of threonine 202 and tyrosine 204 (of human MAP kinase) (3). Erk1 is also known to autophosphorylate on tyrosine (3).
Related Pathway	Adherens junction Delta-Notch Signaling Pathway EGFR1 Signaling Pathway Focal Adhesion MAPK signaling pathway Melanogenesis TGF Beta Signaling Pathway Toll-like receptor signaling pathway Wnt Signaling Pathway

Related Lysate from OriGene • Transient overexpression lysate of mitogen-activated protein kinase 3 (MAPK3), transcript variant 1 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • MAPK3 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • MAPK3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Mapk3 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • MAPK3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Mapk3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 1 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 1 as transfection-ready DNA • Lenti ORF clone of Human mitogen-activated protein kinase 3 (MAPK3), transcript variant 1 , Myc-DDK-tagged • Lenti ORF clone of Human mitogen-activated protein kinase 3 (MAPK3), transcript variant 1, mGFP tagged • Myc-DDK-tagged ORF clone of Homo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 1 as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens mitogen-activated protein kinase 3 (MAPK3), transcript variant 1 as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)