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Home Antibody All anti-MAPK14 antibodies

Anti-MAPK14 Antibody Y122

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SKU Description Amount Price Availability*  
TA300478
  • Rabbit Monoclonal Antibody against MAPK14 (Clone Y122)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400523) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for MAPK14 (NM_001315)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human p38 MAP kinase was used as immunogen. Predicted to react with CSBP1 splice form based on sequence homology.
Clone NameY122 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IHC-P: Use at an assay dependent dilution
Predicted MW Explanation 41 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase 14 (MAPK14), transcript variant 1
Alternative NameCSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; p38; p38ALPHA; PRKM14; PRKM15; RK; SAPK2A
Database LinkNP_001306
Entrez Gene 1432 Human
Entrez Gene 26416 Mouse
Entrez Gene 81649 Rat
Functionp38 MAP kinase is a mitogen-activated protein kinase that functions in various intracellular signaling cascades controlling cellular stress responses. p38 MAP kinase is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharides (LPS), UV light and growth factors (1-3). MKK3 and SEK activate p38 MAP kinase by phosphorylation at adjacent threonine and tyrosine residues, Thr180 and Tyr182 (3,4). Activated p38 MAP kinase phosphorylates numerous downstream targets, including transcription factor ATF-2 (4).
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayVEGF signaling pathwayToll-like receptor signaling pathwayNOD-like receptor signaling pathwayRIG-I-like receptor signaling pathwayT cell receptor signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - p38 antibody [Y122]; All lanes : Anti-p38 antibody [Y122] at 1/50000 dilution.Lane 1 : Hela cell lysate.Lane 2 : Jurkat cell lysate.Lane 3 : K562 cell lysate.Lane 4 : MCF7 cell lysate.Predicted band size : 41 kDa.Observed band size : 42 kDa .
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Immunohistochemistry (Paraffin-embedded sections) - p38 antibody [Y122]; Ab32142, at a 1/100 dilution, staining p38 in paraffin embedded human skin carcinoma tissue by immunohistochemistry.
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Immunofluorescence - p38 antibody [Y122]; Ab32142, at a 1/100 dilution, staining p38 in MCF7 cells by Immunofluorescence.
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