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Anti-MAP2K3 Antibody EP555Y
Also for MAP2K3 (NM_145109)
|A synthetic peptide corresponding to residues in the N-terminus of human MKK3 was used as immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||IP: 1:50; WB: 1:5000 - 1:20000; FC: 1:20
|Does not react with Mouse, Rat. Is unsuitable for ICC or IHC.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for ICC or IHC.
|Homo sapiens mitogen-activated protein kinase kinase 3 (MAP2K3), transcript variant B|
|MAPKK3; MEK3; MKK3; PRKMK3; SAPKK-2; SAPKK2|
|Mitogen-acitvated protein kinase kinase 3 (MKK3) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MAPKs require dual phosphorylation on threonine and tyrosine residues, an activation step carried out by MAPK kinase (1-2). MKK3, closely related to MKK6, efficiently phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines and environmental stress but not JNK or ERK (3). MKK3 is activated by mitogenic and environ-mental stress stimulus as well as by insulin. MKK3 is necessary for the expression of glucose transporter and participates in the MAP kinase- mediated signaling cascade (4).|
EGFR1 Signaling Pathway
MAPK signaling pathway
Senescence and Autophagy
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway
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Western blot - MEK3 antibody [EP555Y]; All lanes : Anti-MEK3 antibody [EP555Y] at 1/20000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : Hela cell lysate.Lane 3 : MCF-7 cell lysate.Lane 4 : K562 cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 39 kDa.Observed band size : 40 kDa .