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Home Antibody All anti-MAP2K2 antibodies

Anti-MAP2K2 TRUEMAB Antibody Clone 1A2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA505680
  • MAP2K2 (MEK2 ) mouse monoclonal antibody, Clone 1A2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403069) , 20ug
100ul 379 In Stock
CF505680
  • Carrier-free (BSA/glycerol-free) MAP2K2 mouse monoclonal antibody,clone 1A2
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
IHC(6)
IF(1)
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Also for MAP2K2 (NM_030662)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human MAP2K2(NP_109587) produced in HEK293T cell.
Clone NameClone 1A2 IsotypeIgG2a
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:200~4000, IHC 1:150, IF 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase kinase 2 (MAP2K2)
Alternative NameCFC4; MAPKK2; MEK2; MKK2; PRKMK2
Database LinkNP_109587
FunctionThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008].
Related Pathway
EGFR1 Signaling Pathway
Focal Adhesion
MAPK signaling pathway
Melanogenesis
Toll-like receptor signaling pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MAP2K2 (RC201827, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MAP2K2.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-MAP2K2 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-MAP2K2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505680)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-MAP2K2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505680)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-MAP2K2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505680)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-MAP2K2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505680)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-MAP2K2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505680)
IHC Image
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-MAP2K2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505680)
IF Image
Anti-MAP2K2 mouse monoclonal antibody (TA505680) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAP2K2(RC201827).

 

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