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Anti-MAGEA1 Antibody EPR4276
Also for MAGEA1 (NM_004988)
|A synthetic peptide corresponding to residues in human MAGE 1 was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; ICC: 1:100 - 1:250; FC: 1:10 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for IHC-P or IP.
|Homo sapiens melanoma antigen family A, 1 (directs expression of antigen MZ2-E) (MAGEA1)|
|MAGE1 (Melanoma-associated antigen 1) is an antigen recognized on a melanoma by autologous cytolytic T-lymphocytes (1). It may play a role in embryonal development and tumor transformation or aspects of tumor progression (1). MAGE 1 is specifically expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes (1). It is never expressed in kidney tumors, leukemias and lymphomas (1). MAGE 1 has been implicated in some hereditary disorders, such as dyskeratosis congenital (2).|
Delta-Notch Signaling Pathway
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Western blot - MAGE 1 antibody [EPR4276]; All lanes : Anti-MAGE 1 antibody [EPR4276] at 1/1000 dilution.Lane 1 : A375 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : Jurkat cell lysate.Lane 4 : HepG2 cell lysate.Lane 5 : MCF7 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 34 kDa.Observed band size : 46 kDa .