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Home Antibody All anti-MAEL antibodies

Anti-MAEL Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306950
  • Rabbit Polyclonal Maelstrom Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC409892) , 20ug
100ug $325 3-7 Days
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WB(1)
IF(2)

OriGene Data

ImmunogenMaelstrom antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Maelstrom.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/ml, ICC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens maelstrom spermatogenic transposon silencer (MAEL), transcript variant 1
Alternative NameCT128; SPATA35
Database LinkNP_116247
FunctionThe mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5’-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
Related Pathway

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WB Image
Western blot analysis of Maelstrom in HeLa cell lysate with Maelstrom antibody at 1 ug/mL.
IF Image
Immunocytochemistry of Maelstrom in HeLa cells with Maelstrom antibody at 5 ug/mL.
IF Image
Immunofluorescence of Maelstrom in HeLa cells with Maelstrom antibody at 20 ug/mL.

 

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