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Home Antibody All anti-MAEL antibodies

Anti-MAEL Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306950 Rabbit Polyclonal Maelstrom Antibody 100ug $325 3-7 Days
LC409892 MAEL HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IF(1)

OriGene Data

ImmunogenMaelstrom antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Maelstrom.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/ml, ICC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens maelstrom spermatogenic transposon silencer (MAEL), transcript variant 1
Alternative NameCT128; SPATA35
Database LinkNP_116247
Entrez Gene 84944 Human
Entrez Gene 98558 Mouse
Entrez Gene 364039 Rat
FunctionThe mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5’-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of Maelstrom in HeLa cell lysate with Maelstrom antibody at 1 ug/mL.
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Immunofluorescence of Maelstrom in HeLa cells with Maelstrom antibody at 20 ug/mL.
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