Home Antibody All anti-MAEL antibodies
Also for MAEL (NM_032858)
|Maelstrom antibody was raised against a 16 amino acid peptide near the carboxy terminus of human Maelstrom.|
|Human, Mouse, Rat
||WB: 1 ug/ml, ICC: 5 ug/ml, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens maelstrom spermatogenic transposon silencer (MAEL), transcript variant 1|
Entrez Gene 84944 Human
Entrez Gene 98558 Mouse
Entrez Gene 364039 Rat
|The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5’-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis of Maelstrom in HeLa cell lysate with Maelstrom antibody at 1 ug/mL.
Immunofluorescence of Maelstrom in HeLa cells with Maelstrom antibody at 20 ug/mL.