OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-LYVE1 antibodies

Anti-LYVE1 Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301773
  • Rabbit Polyclonal Antibody against LYVE1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402008) , 20ug
100ul 325 3-7 Days
Add to Shopping Cart
WB(2)
spacer
Also for LYVE1 (NM_006691)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide made to a C-terminal portion of the human LYVE-1 protein sequence (between residues 250-322).
Clone Name IsotypeIgG
Species Reactivityhuman, mouse ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1: 1000
BufferTris-glycine, 150 mM NaCl and .05% Sodium azide
Purification Affinity purified

Reference Data

Target NameHomo sapiens lymphatic vessel endothelial hyaluronan receptor 1 (LYVE1)
Alternative NameCRSBP-1; HAR; LYVE-1; XLKD1
Database LinkNP_006682
FunctionThe lymphatic vasculature forms a second circulatory system that drains extracellular fluid from the tissues and provides an exclusive environment in which immune cells can encounter and respond to foreign antigen. Recently a number of interesting molecules have been identified that may be exploited as markers for lymphatic endothelium, including the hyaluronan receptor LYVE1, PALE, VEGFR3, and podoplanin. LYVE1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module, the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Detection of LYVE-1 in recombinant human protein, ECL detection overnight
WB Image
Western Blot: LYVE1 Antibody - Detection of LYVE-1 in mouse spleen lysate. ECL detection overnight.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title