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Home Antibody All anti-LY96 antibodies

Anti-LY96 Antibody 1A2E3

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319869
  • Mouse MD-2 Monoclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC414593) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenMouse monoclonal MD-2 antibody was raised against a recombinant protein corresponding to amino acids 2 to 160 of human MD-2
Clone Name1A2E3 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsELISA, WB: 1 ug/ml, IHC: 2.5 ug/ml
BufferMD-2 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Purification MD-2 Monoclonal Antibody is immunoaffinity chromotography purified IgG.

Reference Data

Target NameHomo sapiens lymphocyte antigen 96 (LY96), transcript variant 2
Alternative NameESOP-1; ly-96; MD-2; MD2
Database LinkNP_001182726
Entrez Gene 23643 Human
Entrez Gene 17087 Mouse
Entrez Gene 448830 Rat
FunctionMD-2 Monoclonal Antibody: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
Related PathwaySecreted Protein Toll-like receptor signaling pathwayPathogenic Escherichia coli infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of (A) 25 and (B) 125 ng of MD-2 recombinant protein with MD-2 antibody at 1 ug/mL.
IHC Image
Immunohistochemistry of MD-2 in human spleen with MD-2 antibody at 2.5 ug/mL.

 

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