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Home Antibody All anti-LY96 antibodies

Anti-LY96 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306161 Rabbit Polyclonal MD-2 Antibody 100ug $325 3-7 Days
LC414593 LY96 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(1)

OriGene Data

ImmunogenMD-2 antibody was raised against a peptide corresponding to amino acids near the middle region of human MD-2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens lymphocyte antigen 96 (LY96), transcript variant 1
Alternative NameESOP-1; ly-96; MD-2; MD2
Database LinkNP_056179
Entrez Gene 23643 Human
Entrez Gene 17087 Mouse
Entrez Gene 448830 Rat
FunctionMD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1-3). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS (5,6). The specificity of this response is determined by the species of MD-2; e.g., human MD-2 can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4 (7).
Related PathwaySecreted Protein Toll-like receptor signaling pathwayPathogenic Escherichia coli infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of MD-2 in mouse spleen cell lysate with MD-2 antibody at 1 ug/ml.
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Immunohistochemical staining of rat spleen cells using MD-2 antibody at 2 ug/ml.
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