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Home Antibody All anti-LY9 antibodies

Anti-LY9 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319679
  • Rabbit Polyclonal SLAMF3 Antibody
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for LY9 (NM_002348)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSLAMF3 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SLAMF3.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 - 2 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
BufferSLAMF3 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification SLAMF3 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens lymphocyte antigen 9 (LY9), transcript variant 1
Alternative NameCD229; hly9; mLY9; SLAMF3
Database LinkNP_002339
Entrez Gene 4063 Human
Entrez Gene 17085 Mouse
Entrez Gene 289227 Rat
FunctionSLAMF3 Antibody: The signaling lymphocyte-activation molecule family member 3 (SLAMF3), also known as LY9, is a cell surface receptor that is expressed on T and B lymphocytes and belongs to the CD150/SLAMF1 receptor family. SLAMF3 was identified through a yeast two-hybrid screening in which SLAMF3 bound to the X-linked lymphoproliferative disease gene product SAP, suggesting that in activated T cells, SLAMF3 signaling can be triggered SAP. Its expression on the cell surface appears to be regulated via its interaction with the clathrin-associated adaptor complex 2 (AP-2). Despite its similarity to SLAMF1 in structure and interactions with SAP, SLAMF3-deficient mice do not exhibit phenotypic characteristics associated with SLAMF1- and SAP-deficient mice, suggesting that SLAMF3 plays other roles in T cell activation.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of SLAMF3 in 293 cell lysate with SLAMF3 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunofluorescence of SLAMF3 in 293 cells with SLAMF3 antibody at 20 ug/mL.

 

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