Home Antibody All anti-LTBP4 antibodies
Also for LTBP4 (NM_001042545)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 64 and 256 of LTBP-4|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens latent transforming growth factor beta binding protein 4 (LTBP4), transcript variant 3|
|ARCL1C; LTBP-4; LTBP4L; LTBP4S|
Entrez Gene 8425 Human
Entrez Gene 108075 Mouse
|Transforming growth factor-beta, or TGFB (see TGFB1; MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP). TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1; MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF; MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797). See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]|
|Druggable Genome |
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A: Hela B: JurKat (anti-LTBP4 antibody diluted at 1:1000)
A: Mouse brain (anti-LTBP4 antibody diluted at 1:1000)
Immunofluorescence analysis of methanol-fixed A431, using LTBP4(anti-LTBP4 antibody) antibody at 1:200 dilution.