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Home Antibody All anti-LRRTM2 antibodies

Anti-LRRTM2 Antibody Polyclonal

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SKU Description Amount Price Availability*  
TA319881 Rabbit Polyclonal LRRTM2 Antibody 100ug $325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for LRRTM2 (NM_015564)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenLRRTM2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRTM2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferLRRTM2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification LRRTM2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens leucine rich repeat transmembrane neuronal 2 (LRRTM2)
Alternative NameFLJ76283; FLJ99831
Database LinkNP_056379
Entrez Gene 26045 Human
Entrez Gene 107065 Mouse
Entrez Gene 685472 Rat
FunctionLRRTM2 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critical role in regulatory excitatory synapse development.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of LRRTM2 in SK-N-SH cell lysate with LRRTM2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of LRRTM2 in human brain tissue with LRRTM2 antibody at 2.5 ug/mL.
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Immunofluorescence of LRRTM2 in human brain tissue with LRRTM2 antibody at 20 ug/mL.
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