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Home Antibody All anti-LRRFIP1 antibodies

Anti-LRRFIP1 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319771
  • Rabbit Polyclonal LRRFIP1 Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for LRRFIP1 (NM_004735)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenLRRFIP1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human LRRFIP1.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferLRRFIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification LRRFIP1 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), transcript variant 4
Alternative NameFLAP-1; FLAP1; FLIIAP1; GCF-2; GCF2; HUFI-1; TRIP
Database LinkNP_004726
FunctionLRRFIP1 Antibody: LRRFIP1, also known as GC-binding factor 2 (GCF2), is a 738 amino acid transcriptional repressor that mainly plays a cytoskeletal role. It is primarily localized in the cytoplasm and preferentially binds to GC-rich dsDNA, but will also bind directly to dsRNA as well. The RNA binding domain encompasses a lysine-rich motif. LRRFIP1 interacts with the mammalian Flightless I (Fli-I) and is a key component in the cytoskeletal regulation of platelet function. LRRFIP1 and the related protein LRRFIP2 may modulate canonical WNT signaling and mediate the IRF3-induced production of type I interferon via a beta-catenin-dependent pathway.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LRRFIP1 in human colon tissue lysate with LRRFIP1 antibody at 1 ug/mL.
IHC Image
Immunohistochemistry of LRRFIP1 in human colon tissue with LRRFIP1 antibody at 5 ug/mL.
IF Image
Immunofluorescence of LRRFIP1 in human colon tissue with LRRFIP1 antibody at 20 ug/mL.

 

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