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Anti-LRRFIP1 Antibody Polyclonal
Also for LRRFIP1 (NM_004735)
|LRRFIP1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human LRRFIP1.|
||ELISA, WB: 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
|LRRFIP1 Antibody is supplied in PBS containing 0.02% sodium azide.|
|LRRFIP1 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens leucine rich repeat (in FLII) interacting protein 1 (LRRFIP1), transcript variant 4|
|FLAP-1; FLAP1; FLIIAP1; GCF-2; GCF2; HUFI-1; TRIP|
|LRRFIP1 Antibody: LRRFIP1, also known as GC-binding factor 2 (GCF2), is a 738 amino acid transcriptional repressor that mainly plays a cytoskeletal role. It is primarily localized in the cytoplasm and preferentially binds to GC-rich dsDNA, but will also bind directly to dsRNA as well. The RNA binding domain encompasses a lysine-rich motif. LRRFIP1 interacts with the mammalian Flightless I (Fli-I) and is a key component in the cytoskeletal regulation of platelet function. LRRFIP1 and the related protein LRRFIP2 may modulate canonical WNT signaling and mediate the IRF3-induced production of type I interferon via a beta-catenin-dependent pathway.|
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Western blot analysis of LRRFIP1 in human colon tissue lysate with LRRFIP1 antibody at 1 ug/mL.
Immunohistochemistry of LRRFIP1 in human colon tissue with LRRFIP1 antibody at 5 ug/mL.