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Anti-LRPAP1 Antibody EPR3327
Also for LRPAP1 (NM_002337)
|A synthetic peptide corresponding to residues in human LRPAP1 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:500~2000; IHC: 1: 100~250; FC: 1:20
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Homo sapiens low density lipoprotein receptor-related protein associated protein 1 (LRPAP1), transcript variant 1|
|A2MRAP; A2RAP; alpha-2-MRAP; HBP44; MRAP; MYP23; RAP|
Entrez Gene 4043 Human
Entrez Gene 16976 Mouse
Entrez Gene 116565 Rat
|The low density lipoprotein receptor-related protein-associated protein 1 (LRPAP1/RAP) is an antagonist and molecular chaperone protein that binds tightly to low-density lipoprotein receptor family members and thereby prevents the binding of all known ligands, including alpha 2-macroglobulin and chylomicron remnants. LRPAP1 is present on the cell surface where it is an effective inhibitor of ligand binding to the kidney glycoprotein 330 (gp330), but is most abundant in the endoplasmic reticulum lumen and may function in receptor folding and/or trafficking (1-3). |
|TransmembraneDruggable Genome |
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Western blot - LRPAP1 antibody [EPR3327]; All lanes : Anti-LRPAP1 antibody [EPR3327] at 1/2000 dilution.Lane 1 : fetal kidney lysate .Lane 2 : mouse kidney lysate.Lane 3 : rat kidney lysate.Lane 4 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Secondary.goat anti-rabbit HRP labeled IgG at 1/2000 dilution.Predicted band size : 41 kDa.Observed band size : 45 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - LRPAP1 antibody [EPR3327]; Immunohistochemical analysis of paraffin-embedded human brain tissue using TA301347, at 1/100-1/250 dilution.