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Anti-LPAR1 TRUEMAB Antibody clone 1G6
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for LPAR1 (NM_001401)
|Full length human recombinant protein of human LPAR1(NP_001392) produced in HEK293T cell.|
|WB, IF, FC
|| WB 1:2000, IF 1:100, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens lysophosphatidic acid receptor 1 (LPAR1), transcript variant 1|
|edg-2; EDG2; Gpcr26; GPR26; LPA1; Mrec1.3; rec.1.3; vzg-1; VZG1|
|The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul |
Signaling by GPCR
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LPAR1 (RC206065, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LPAR1.
Anti-LPAR1 mouse monoclonal antibody (TA503737) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LPAR1(RC206065).
HEK293T cells transfected with either RC206065 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-LPAR1 antibody(TA503737), and then analyzed by flow cytometry.