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Anti-LPA Antibody EPR6474
|A synthetic peptide corresponding to residues in human Apolipoprotein(a) was used as an immunogen.|
||Tissue culture supernatant
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000; IHC-P: 1:100 - 1:250
|pH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA|
|Is unsuitable for IP.
|Homo sapiens lipoprotein, Lp(a) (LPA)|
|AK38; APOA; LP|
Entrez Gene 4018 Human
|Apolipoprotein(a) is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. It constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of Apolipoprotein(a) are linked to atherosclerosis. Depending on the individual, it contains 2-43 copies of kringle-type domains (1).|
|Druggable Genome |
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Western blot - Anti-Lipoprotein a antibody [EPR6474]; Anti-Lipoprotein a antibody [EPR6474] at 1/20000 dilution + Human plasma lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 501 kDa.Observed band size : 500 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Lipoprotein a antibody [EPR6474]; TA310972 at 1/100 staining Lipoprotein a in paraffin embedded Human kidney tissue by immunohistochemistry.