OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-LOX antibodies

Anti-LOX TRUEMAB Antibody clone 4E3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500865
  • LOX mouse monoclonal antibody, clone 4E3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400843) , 20ug Explanation
100ul 325 In Stock
CF500865
  • Carrier-free (BSA/glycerol-free) LOX mouse monoclonal antibody, clone 4E3
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
Add to Shopping Cart
WB(1)
IHC(1)
IF(1)
FC(1)
spacer
Also for LOX (NM_002317)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cell.
Clone Nameclone 4E3 IsotypeIgG1
Species ReactivityHuman Concentration0.42 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500, IHC 1:50, IF 1:100, FLOW 1:100,
Predicted MW Explanation 46.8 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens lysyl oxidase (LOX), transcript variant 1
Alternative NameMGC105112
Database LinkNP_002308
Entrez Gene 4015 Human
FunctionThe protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwaySecreted ProteinDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LOX (RC213323, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LOX.
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-LOX mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500865)
IF Image
Anti-LOX mouse monoclonal antibody (TA500865) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LOX(RC213323).
FC Image
HEK293T cells transfected with either RC213323 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-LOX antibody(TA500865), and then analyzed by flow cytometry.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title