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Home Antibody All anti-LOX antibodies

Anti-LOX Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301450
  • Rabbit Polyclonal Antibody against LOX
100ul 325 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenTwo synthetic peptides (a.a. 181-196 and 293-309) of the rat LOX protein.
Clone Name IsotypeIgG
Species ReactivityMouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:4000
Buffer0.1% sodium azide
Purification Whole antisera

Reference Data

Target NameRattus norvegicus lysyl oxidase (Lox)
Alternative NameH-rev142; Rrg1
Database LinkNP_058757
FunctionLysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.
Related Pathway

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WB Image
Detection of LOX protein, Lane 1: Twice extracted guanidine hydrochloride mouse tibia/fibula lysate., Lane 2: normal rabbit serum
IHC Image
Staining of LOX in mouse spleen

 

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