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Home Antibody All anti-LOX antibodies

Anti-LOX Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA301449 Rabbit Polyclonal Antibody against LOX 100ul $325 3-7 Days
LC400843 LOX HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide made to an internal region of the human LOX protein (within residues 200-300). [Swiss-Prot P28300]
Clone Name IsotypeIgG
Species Reactivityhuman, mouse Concentration0.62 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5-4 ug/ml
BufferTris-glycine, 150mM NaCl and 0.05% sodium azide
Purification Affinity purified

Reference Data

Target NameHomo sapiens lysyl oxidase (LOX), transcript variant 1
Alternative NameMGC105112
Database LinkNP_002308
Entrez Gene 4015 Human
Entrez Gene 16948 Mouse
FunctionLysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.
Related PathwaySecreted ProteinDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Detection of LOX in human kidney lysate

IHC Image
Staining of LOX in mouse stomach


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