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Home Antibody All anti-LMX1B antibodies

Anti-LMX1B Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319063
  • Rabbit polyclonal anti-LMX1B antibody (CT)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419399) , 20ug Explanation
100ug 345 3-7 Days
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WB(1)

OriGene Data

ImmunogenRabbit polyclonal LMX1B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LMX1B.
Clone Name IsotypeRabbit IgG1
Species ReactivityHuman, Mouse, Rat Concentration1 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-2 ug/ml, ELISA
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens LIM homeobox transcription factor 1, beta (LMX1B), transcript variant 1
Alternative NameLMX1.2; NPS1
Database LinkNP_002307
Entrez Gene 4010 Human
Entrez Gene 16917 Mouse
Entrez Gene 114501 Rat
FunctionThe LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning; LMX1B- mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LMX1B in A-20 cell lysate with LMX1B antibody at (A) 1 and (B) 2 µg/mL.

 

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