Home Antibody All anti-LMX1B antibodies
Also for LMX1B (NM_002316)
|Rabbit polyclonal LMX1B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human LMX1B.|
|Human, Mouse, Rat
||WB: 1-2 ug/ml, ELISA
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Affinity chromatography purified via peptide column
|Homo sapiens LIM homeobox transcription factor 1, beta (LMX1B), transcript variant 1|
Entrez Gene 4010 Human
Entrez Gene 16917 Mouse
Entrez Gene 114501 Rat
|The LIM homeobox transcription factor 1B (LMX1B) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1B regulates mid-hindbrain patterning; LMX1B- mice embryos have a severe reduction in the number of midbrain dopaminergic neurons compared to wild-type. While LMX1B appears to be important for both the development and the survival of dopamine neurons, the related LMX1A is crucial for the differentiation of these cells. However, LMX1A and LMX1B function cooperatively to regulated the proliferation, specification and differentiation of midbrain dopaminergic neuronal progenitors|
|Transcription Factors |
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Western blot analysis of LMX1B in A-20 cell lysate with LMX1B antibody at (A) 1 and (B) 2 µg/mL.