Home Antibody All anti-LMX1A antibodies
Also for LMX1A (NM_177399)
|Rabbit polyclonal LMX1A antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LMX1A.|
|Human, Mouse, Rat
||WB: 1-2 ug/ml, ELISA
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Affinity chromatography purified via peptide column
|Homo sapiens LIM homeobox transcription factor 1, alpha (LMX1A), transcript variant 2|
|LMX-1; LMX1; LMX1.1; MGC87616;sst; Lmx1.1; MGC129356; MGC129357; dr; dreher; OTTMUSP00000022889; OTTMUSP00000022890; shaker short-tail; LIM homeobox transcription factor 1 alpha|
|The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.|
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Western blot analysis of LMX1A in rat brain tissue lysate with LMX1A antibody at (A) 1 and (B) 2 µg/mL.