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Home Antibody All anti-LMO2 antibodies

Anti-LMO2 Antibody EP3257

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307207 Rabbit monoclonal antibody against LMO2(clone EP3257) 100ul $325 In Stock
LC432149 LMO2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
FC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human LMO2 was used as an immunogen.
Clone NameEP3257 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsFC: 1:100 - 500, IP: 1:100 - 500, WB: 1:1000 - 10,000,
Predicted MW Explanation 18 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%

Reference Data

Target NameHomo sapiens LIM domain only 2 (rhombotin-like 1) (LMO2), transcript variant 1
Alternative NameRBTN2; RBTNL1; RHOM2; TTG2
Database LinkNP_005565
Entrez Gene 4005 Human
Entrez Gene 16909 Mouse
Entrez Gene 362176 Rat
FunctionLMO2 (LIM-only protein 2, RBNT2), a member of the LIM-only class of transcriptional co-regulators that consist of two closely spaced cysteine-rich LIM domains has distinct functions in erythropoiesis and in T-cell leukemogenesis. These diverse functions of LMO2 are presumed to be accomplished through physical interaction with different with different protein partners that bind the LIM domains of LMO2 (1). It is also required for early stages of hematopoiesis, and the LMO2 master gene encodes a protein that has a central and crucial role in the hematopoietic development (2). LMO2 has been identified as a novel oncogene associated with carcinogenesis and prognosis in several malignant tumors (3)
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - LMO2 antibody [EP3257]; All lanes : Anti-LMO2 antibody [EP3257] at 1/1000 dilution.Lane 1 : Raji cell lysate.Lane 2 : Fetal kidney lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 18 kDa.
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Flow Cytometry - Anti-LMO2 antibody; Overlay histogram showing Ramos cells stained with TA307207 (red line). The secondary antibody used was Alexa Fluor 488 goat anti-rabbit IgG (H+L) at 1:2000. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1ug/1x10^6 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. This antibody gave a positive signal in Ramos cells under the same conditions.
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