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Home Antibody All anti-LMAN1 antibodies

Anti-LMAN1 TRUEMAB Antibody Clone OTI2B10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA502110 LMAN1 mouse monoclonal antibody, clone OTI2B10 (formerly 2B10) 100ul $325 In Stock
LC401709 LMAN1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF502110 Carrier-free (BSA/glycerol-free) LMAN1 mouse monoclonal antibody, clone OTI2B10 (formerly 2B10) 100ug $450 3-4 weeks
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WB(2)
IF(1)
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Also for LMAN1 (NM_005570)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human LMAN1 (NP_005561) produced in HEK293T cell.
Clone NameClone OTI2B10 IsotypeIgG1
Species ReactivityHuman, Monkey Concentration0.59 mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:200~500, IF 1:100,
Predicted MW Explanation 54.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens lectin, mannose-binding, 1 (LMAN1)
Alternative NameERGIC-53; ERGIC53; F5F8D; FMFD1; gp58; MCFD1; MR60
Database LinkNP_005561
Entrez Gene 3998 Human
Entrez Gene 697449 Monkey
FunctionThe protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq].
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LMAN1 (RC207088, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LMAN1.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-LMAN1 monoclonal antibody.
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Anti-LMAN1 mouse monoclonal antibody (TA502110) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY LMAN1(RC207088).
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