Home Antibody All anti-LITAF antibodies
Also for LITAF (NM_001136473)
|Recombinant fragment corresponding to a region within amino acids 1 and 161 of LITAF (Uniprot ID#Q99732)|
|Human (Predicted: Mouse, Rat, Bovine)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (85%), Rat (86%), Bovine (86%)
|Homo sapiens lipopolysaccharide-induced TNF factor (LITAF), transcript variant 3|
|PIG7; SIMPLE; TP53I7|
Entrez Gene 9516 Human
Entrez Gene 56722 Mouse
Entrez Gene 65161 Rat
|Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]|
|Transcription FactorsDruggable Genome |
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Sample (30 ug of whole cell lysate). A: Hep G2 . 12% SDS PAGE. TA308382 diluted at 1:1000
LITAF antibody [N1C3] detects LITAF protein at cytoplasm on placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. LITAF antibody [N1C3] (TA308382) dilution: 1:100.