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Home Antibody All anti-LITAF antibodies

Anti-LITAF Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308382
  • Rabbit polyclonal antibody to LITAF (lipopolysaccharide-induced TNF factor)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC427884) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for LITAF (NM_001136473)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 161 of LITAF (Uniprot ID#Q99732)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Mouse (85%), Rat (86%), Bovine (86%)

Reference Data

Target NameHomo sapiens lipopolysaccharide-induced TNF factor (LITAF), transcript variant 3
Alternative NamePIG7; SIMPLE; TP53I7
Database LinkNP_001129945
Entrez Gene 9516 Human
Entrez Gene 56722 Mouse
Entrez Gene 65161 Rat
FunctionLipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Hep G2 . 12% SDS PAGE. TA308382 diluted at 1:1000
IHC Image
LITAF antibody [N1C3] detects LITAF protein at cytoplasm on placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. LITAF antibody [N1C3] (TA308382) dilution: 1:100.

 

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