Home Antibody All anti-LIPG antibodies
Also for LIPG (NM_006033)
|A C-terminal synthetic peptide made to the human endothelial lipase protein sequence.|
|Homo sapiens lipase, endothelial (LIPG)|
|EDL; EL; PRO719|
Entrez Gene 9388 Human
|Endothelial lipase (EL) is a novel member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and functions at the site of synthesis. EL most likely plays a physiological role in modulating lipoprotein metabolism. Overexpressed EL has been shown to reduce HDL cholesterol levels, whereas an EL deficiency appears to be effective in elevating HDL cholesterol levels in animals.|
|Secreted ProteinDruggable Genome Glycerolipid metabolismMetabolic pathways|
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Human endothelial lipase detected in transfected 293 lysates (MW 57 kDa)
Western Blot: Endothelial Lipase Antibody- Cells were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY LIPG cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted.
Immunocytochemistry/Immunofluorescence: Endothelial Lipase Antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).