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Home Antibody All anti-LIPE antibodies

Anti-LIPE Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306363 Rabbit Polyclonal Lipe Antibody 100ug $325 3-7 Days
LC417354 LIPE HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenLipe antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human lipe.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 0.5 - 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens lipase, hormone-sensitive (LIPE)
Alternative NameAOMS4; FPLD6; HSL; LHS
Database LinkNP_005348
Entrez Gene 3991 Human
Entrez Gene 16890 Mouse
Entrez Gene 25330 Rat
FunctionAlthough initially described as an adipocyte-specific triacylglycerol lipase, lipe (also known as hormone-specific lipase or HSL) is expressed in multiple tissues and cell lines. It plays multiple roles in lipid metabolism, including hormone-stimulated lipolysis in adipose tissue and the hydrolysis of cholesterol esters. Lipe is expressed as a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesterol esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. Recently, it was observed that the lack of lipe in genetically obese leptin-null mice inhibited obesity and adipogenesis, suggesting that lipe plays a major role in adipocyte proliferation.
Related Pathway Insulin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of lipe in human lymph node tissue lysate with lipe antibody at (A) 0.5 and (B) 1 ug/ml.

IHC Image
Immunohistochemistry of lipe in human lymph node tissue with lipe antibody at 2.5 ug/ml.

IF Image
Immunofluorescence of Lipe in Human Lymph Node cells with Lipe antibody at 20 ug/mL.


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