OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-LIPE antibodies

Anti-LIPE Antibody EPR2330

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301368
  • Rabbit Monoclonal Antibody against LIPE (Clone EPR2330)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417354) , 20ug
100ul $325 3-7 Days
Add to Shopping Cart
WB(1)
spacer
Also for LIPE (NM_005357)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA phospho-specific peptide corresponding to residues surrounding Serine 855 of human HSL was used as an immunogen. The antibody only detects HSL phosphorylated on Serine 855.
Clone NameEPR2330 IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1: 1,000~5,000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Rat

Reference Data

Target NameHomo sapiens lipase, hormone-sensitive (LIPE)
Alternative NameHSL; LHS
Database LinkNP_005348
FunctionHormone-sensitive lipase (HSL) is a key enzyme in fatty acid mobilization, overall energy homeostasis, and possibly steroidogenesis. It is acutely controlled through reversible phosphorylation by catecholamines and insulin (1). HSL is the rate-limiting enzyme in hydrolysis of triglycerides in adipose tissue and of cholesteryl esters in steroidogenic tissues including the adrenals, ovaries, testes, and macrophages (2, 3). HSL activity has been positively correlated with free and esterified cholesterol ratios in seminiferous tubules (STf) and interstitial tissue (ITf) enriched fractions, but not with triglyceride levels, during testicular development. HSL is localized to elongated spermatids and Sertoli cells, where its distribution is stage-dependent, and within the cells lining the excurrent ducts of the testis. The HSL protein levels and enzymatic activity in ITf and STf were reported positively correlated with serum testosterone levels during development (4).
Related Pathway
Adipogenesis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - HSL/LIPE (phospho S855) antibody [EPR2330]; All lanes : Anti-Hormone sensitive lipase (phospho S855) antibody [EPR2330] at 1/5000 dilution.Lane 1 : Human skeletal muscle lysate, untreated.Lane 2 : Human skeletal muscle lysate, treated with LP.Lysates/proteins at 10 µg per lane.Secondary.HRP labeled goat anti-rabbit at 1/1000 dilution.Predicted band size : 117 , 83 kDa.Observed band size : 83 kDa .

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title