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Home Antibody All anti-LINGO1 antibodies

Anti-LINGO1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA302273
  • Rabbit Polyclonal Antibody against LINGO1 (N-term)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC409935) , 20ug Explanation
100ug $325 In Stock
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WB(1)
IHC(1)
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Also for LINGO1 (NM_032808)
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OriGene Data

ImmunogenThis LINGO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-92 amino acids from the N-terminal region of human LINGO1.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman (Predicted: Mouse, Chicken, Monkey) Concentration0.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000, IHC: 1:10~50
Predicted MW Explanation 69876 Da
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens leucine rich repeat and Ig domain containing 1 (LINGO1), transcript variant 1
Alternative NameLERN1; LRRN6A; UNQ201
Database LinkNP_116197
Entrez Gene 84894 Human
Entrez Gene 235402 Mouse
Entrez Gene 714985 Monkey
FunctionLINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.
Related PathwayTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of LINGO1 (arrow) using rabbit polyclonal LINGO1 Antibody (N-term) (Cat.#TA302273).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the LINGO1 gene (Lane 2) (Origene Technologies).
IHC Image
Formalin-fixed and paraffin-embedded human brain tissue reacted with LINGO1 Antibody (N-term) (Cat.#TA302273), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

 

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