OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-LIG3 antibodies

Anti-LIG3 Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308823
  • Rabbit polyclonal antibody to DNA ligase 3 (ligase III, DNA, ATP-dependent)
100ul 325 In Stock
Add to Shopping Cart
WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 116 and 433 of DNA ligase 3 (Uniprot ID#P49916)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1.01mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 113kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens ligase III, DNA, ATP-dependent (LIG3), transcript variant beta
Alternative NameLIG2
Database LinkNP_002302
Entrez Gene 3980 Human
FunctionThis gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Related PathwayDruggable Genome Base excision repair

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
DNA ligase III antibody detects DNA ligase III protein by western blot analysis. Various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with DNA ligase III antibody (TA308823) diluted by 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded A549 Xenograft, using DNA ligase 3(TA308823) antibody at 1:100 dilution.
IF Image
DNA ligase III antibody detects LIG3 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: LIG3 protein stained by DNA ligase III antibody (TA308823) diluted at 1:500. Blue: Hoechst

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title