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Also for LIG3 (NM_002311)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 116 and 403 of DNA ligase 3|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens ligase III, DNA, ATP-dependent (LIG3), transcript variant beta|
|This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]|
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A: HepG2 (anti-LIG3 antibody diluted at 1:1000)
Immunohistochemical analysis of paraffin-embedded A549 Xenograft, using DNA ligase 3(anti-LIG3 antibody) antibody at 1:100 dilution.