Home Antibody All anti-LIF antibodies
|E. coli-expressed recombinant human LIF|
||WB: 0.5-4 ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens leukemia inhibitory factor (LIF), transcript variant 1|
|CDF; DIA; HILDA; MLPLI|
|Leukemia Inhibitory Factor (LIF) is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. LIF has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF. |
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
TGF Beta Signaling Pathway
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Western blot analysis using recombinant human LIF. Lane 1: 100 ng, Lane 2: 200 ng, Lane 3: 500 ng.