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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
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Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-LGR5 antibodies

Anti-LGR5 Conjugated Antibody clone 2A2

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SKU Description Amount Price Availability*  
TA400007
  • Anti-LGR5 mouse mAb, clone 2A2, bionylated
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401213) , 20ug
 50ug $325 In Stock Add to Shopping Cart
WB(1)
Gene NameHomo sapiens leucine-rich repeat containing G protein-coupled receptor 5 (LGR5), transcript variant 1
Synonyms:FEX; GPR49; GPR67; GRP49; HG38
ImmunogenHuman recombinant protein fragment corresponding to amino acids 250-550 of human LGR5 (NP_003658) produced in 293T Cell.
BufferTBS containing 0.1% BSA, 0.05% Sodium Azide and 50% Glycerol
Clone Nameclone 2A2 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:100
BackgroundLGR5 (leucine-rich repeat containing G protein-coupled receptor 5) An Orphan GPCR protein, contains large extracellular domain, Stem cell biomarker for small intestine, active in colon cancer; overexpressed in ovary and liver tumors.
Related Pathway

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WB Image
HEK293T cells were transfected with pCMV6-ENTRY control (Lane 1) or pCMV6-ENTRY LGR5 (Lane 2, 3) plasmids for 48 hrs. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LGR5-Biotin and Streptavidin-HRP (Sample was either boiled [lane 2] or not boiled [lane3] before loading to the gel).

 

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