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Home Antibody All anti-LEFTY2 antibodies

Anti-LEFTY2 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308258 Rabbit polyclonal antibody to Lefty -A (left-right determination factor 2) 100ul $325 3-7 Days
LC418816 LEFTY2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 25 and 366 of LEFTY2 (Uniprot ID#O00292)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Rat) Concentration1.01mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 41kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (83%)

Reference Data

Target NameHomo sapiens left-right determination factor 2 (LEFTY2), transcript variant 1
Alternative NameEBAF; LEFTA; LEFTYA; TGFB4
Database LinkNP_003231
Entrez Gene 7044 Human
Entrez Gene 289316 Rat
FunctionThis gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq]
Related PathwaySecreted ProteinDruggable Genome TGF-beta signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: A431 . 10% SDS PAGE. TA308258 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Colon ca, using LEFTY2(TA308258) antibody at 1:500 dilution.


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