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Home Antibody All anti-LEF1 antibodies

Anti-LEF1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303096
  • Goat Polyclonal Antibody against LEF1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC427260) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for LEF1 (NM_001130713)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

Immunogen Peptide with sequence C-QHEQRKEQEPKRPH, from the internal region of the protein sequence according to NP_057353.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Mouse, Rat. Expected from seq similarity: Human, Mouse, Rat, Dog Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:32,000. WB: 1-3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens lymphoid enhancer-binding factor 1 (LEF1), transcript variant 2
Alternative NameLEF-1; TCF10; TCF1ALPHA; TCF7L3
Database LinkNP_001124185
Entrez Gene 51176 Human
Entrez Gene 16842 Mouse
Entrez Gene 161452 Rat
Entrez Gene 478507 Dog
FunctionLEF1 is a nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha (TCRA; MIM 186880) enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1 (HMG1; MIM 163905) (Waterman et al., 1991 [PubMed 2010090]; van Genderen et al., 1994 [PubMed 7958926]).[supplied by OMIM].
Related PathwayES Cell Differentiation/IPSAdult stem cellsTranscription FactorsDruggable Genome Wnt signaling pathwayAdherens junctionMelanogenesisPathways in cancerColorectal cancerEndometrial cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA303096 (1µg/ml) staining of Daudi cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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