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Home Antibody All anti-LDHA antibodies

Anti-LDHA Antibody EP1563Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300879
  • Rabbit Monoclonal Antibody against LDHA (Clone EP1563Y)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401712) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for LDHA (NM_005566)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human LDH-A was used as immunogen.
Clone NameEP1563Y IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:5000; IP: 1:70; IHC-P: 1:100 - 1:250; FC: 1:30
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens lactate dehydrogenase A (LDHA), transcript variant 1
Alternative NameGSD11; HEL-S-133P; LDH1; LDHM; PIG19
Database LinkNP_005557
FunctionLactate dehydrogenase (LDH) is an ubiquitous enzyme commonly found in wide variety of organisms, including plants and microbes. LDH is involved in the interconversion of the pyruvate and NADH to lactate and NAD+. It is also called Hydroxybutyrate Dehydrogenase (HBD), due to the fact that it can catalyze the oxidation of hydroxybutyrate (1). In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C, forming various terameric isoenzymes (140 kDa). Lactate dehydrogenase A (LDH-A, muscle subunit, LDH-M) is involved in the final step of anaerobic glycoysis and catalyzes the conversion of L-lactate and NAD to pryruvate and NADH. While it is predominantly expressed in muscle tissue, it is hormonally regulated in rodents and overexpressed during mammary gland tumorigenesis (2). A mutation that cause deficiency in LDH-A has been implicated in exertional myoglobinuria (3).
Related Pathway

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WB Image
Western blot - Anti-Lactate Dehydrogenase antibody [EP1563Y]; Anti-Lactate Dehydrogenase antibody [EP1563Y] at 1/1000 dilution + A549 cell lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 37 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Lactate Dehydrogenase antibody [EP1563Y]; Immunohistochemical analysis of paraffin-embedded Human kidney carcinoma labelling Lactate Dehydrogenase with TA300879 at 1/100 dilution.

 

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