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Anti-LCAT Antibody EPR1383(2)
Also for LCAT (NM_000229)
|A synthetic peptide corresponding to residues in human LCAT was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||ICC: 1:100 - 1:250; WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt.
|Homo sapiens lecithin-cholesterol acyltransferase (LCAT)|
Entrez Gene 3931 Human
Entrez Gene 16816 Mouse
Entrez Gene 24530 Rat
|LCAT, the lecithin cholesterol acyltransferase, is an enzyme responsible for the esterification of plasma cholesterol mediating the transfer of an acyl group from lecithin to the 3-hydroxy group of cholesterol (1). In patients with familial LCAT deficiency only trace amounts or no LCAT protein is found in plasma. LCAT reactivity is essential for normal lipoprotein metabolism and for a proper equilibrium between tissue and plasma cholesterol (2). LCAT is a soluble enzyme that converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lyso-phosphatidylcholines on the surface of high-density lipoproteins (3).|
|TransmembraneDruggable Genome Glycerophospholipid metabolism|
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Western blot - LCAT antibody [EPR1383(2)]; All lanes : Anti-LCAT antibody [EPR1383(2)] at 1/1000 dilution.Lane 1 : Human serum lysate.Lane 2 : Human plasma lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 50 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - LCAT antibody [EPR1383(2)]; TA307800, at 1/250 dilution, staining LCAT in paraffin-embedded Human liver tissue by Immunohistochemistry.