Home Antibody All anti-LCAT antibodies
Also for LCAT (NM_000229)
|Carboxy-terminal histidine-tagged human recombinant LCAT purified from the medium of CHO cells overexpressing human LCAT cDNA.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1: 1000
|Whole sera and 0.05% sodium azide|
|Homo sapiens lecithin-cholesterol acyltransferase (LCAT)|
|Lecithin: cholesterol acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations.|
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HEK293T cells were transfected with the pCMV6-ENTRY control or pCMV6-ENTRY LCAT (RC203763) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LCAT.