Home Antibody All anti-LASS6 antibodies
Also for LASS6 (NM_203463)
|LASS6 antibody was raised against a 13 amino acid peptide near the amino terminus of the human LASS6.|
|Human, Mouse, Rat
||WB: 1 - 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens ceramide synthase 6 (CERS6), transcript variant 2|
Entrez Gene 253782 Human
Entrez Gene 241447 Mouse
Entrez Gene 366065 Rat
|The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development. At least two isoforms of LASS6 are known to exist. This antibody is predicted not to cross-react with LASS5.|
|TransmembraneDruggable Genome |
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Western blot analysis of LASS6 in rat brain tissue lysate with LASS6 antibody at (A) 1 and (B) 2 ug/ml.
Immunohistochemistry of LASS6 in mouse brain tissue with LASS6 antibody at 2.5 ug/ml.