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Anti-LAS1L Antibody EPR8989(B)
Also for LAS1L (NM_001170649)
|A synthetic peptide corresponding to residues in human LAS1L was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, FC
||WB: 1:1000 - 1:10000; FC: 1:10 - 1:100
|Does not react with Mouse, Rat. Is unsuitable for ICC,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens LAS1-like (S. cerevisiae) (LAS1L), transcript variant 2|
|dJ475B7.2; Las1-like; RP3-475B7.2|
|LAS1L is a nuclear protein essential for cell proliferation and ribosome synthesis; particularly the biogenesis of the 60S ribosomal subunits (1, 2). It is also required for maturation of the 28S rRNA (1). Depletion of LAS1L has shown to cause nucleolar disorganization and inhibit cell proliferation characterized by a p53-dependent G1 cell by cycle arrest (2). |
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Western blot - Anti-LAS1L antibody [EPR8989(B)]; All lanes : Anti-LAS1L antibody [EPR8989(B)] at 1/1000 dilution.Lane 1 : HCT116 cell lysate.Lane 2 : 293T cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 83 kDa.
Other-Anti-LAS1L antibody [EPR8989(B)](ab133649); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-LAS1L antibody [EPR8989(B)]; Flow cytometrical analysis of LAS1L in permeabilized HeLa cells labelled with ab133649 at a 1/10 dilution (red), or with Rabbit IgG negative control (green).