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Home Antibody All anti-LAMP1 antibodies

Anti-LAMP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306262
  • Rabbit Polyclonal LAMP-1 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417223) , 20ug
100ug $325 In Stock
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WB(1)
IF(1)
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Also for LAMP1 (NM_005561)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenLAMP-1 antibody was raised against a 15 amino acid peptide from near the center of human LAMP-1.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IHC: 20 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens lysosomal-associated membrane protein 1 (LAMP1)
Alternative NameCD107a; LAMPA; LGP120
Database LinkNP_005552
FunctionAutophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2) and is negatively regulated by TOR (Target of rapamycin) (3). A protein recently found to be involved in autophagy, LAMP-2, is a highly glycosylated protein associated with the lysosome (4,5). LAMP-1 shares much homology to LAMP-2 and is thought to have overlapping functions. Mice lacking LAMP-1 had very minor defects compared to those deficient in LAMP-2 expression (6). However, the loss of both proteins resulted in embryonic lethality (7), suggesting that each protein possesses some unique and necessary functions.
Related Pathway

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WB Image
Western blot analysis of LAMP-1 in EL4 cell lysate with LAMP-1 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunofluorescence of LAMP-1 in human colon tissue with LAMP-1 antibody at 20 ug/mL.

 

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