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Home Antibody All anti-L1CAM antibodies

Anti-L1CAM TRUEMAB Antibody clone 1H3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500353
  • L1CAM mouse monoclonal antibody, clone 1H3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400150) , 20ug Explanation
100ul 325 In Stock
CF500353
  • Carrier-free (BSA/glycerol-free) L1CAM mouse monoclonal antibody, clone 1H3
100ug $450 3-4 weeks
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WB(2)
IF(1)
FC(1)
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Also for L1CAM (NM_000425)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human L1CAM (NP_000416) produced in HEK293T cell.
Clone Nameclone 1H3 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:2500~5000, IF 1:100, FLOW 1:100
Predicted MW Explanation 140.0 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1
Alternative NameCAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1
Database LinkNP_000416
Entrez Gene 3897 Human
FunctionThe protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Axon guidanceCell adhesion molecules (CAMs)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY L1CAM (RC211601, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-L1CAM.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-L1CAM monoclonal antibody.
IF Image
Anti-L1CAM mouse monoclonal antibody (TA500353) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY L1CAM(RC211601).
FC Image
HEK293T cells transfected with either RC211601 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-L1CAM antibody(TA500353), and then analyzed by flow cytometry.

 

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