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Home Antibody All anti-L1CAM antibodies

Anti-L1CAM TRUEMAB Antibody clone 10C12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA500334
  • L1CAM mouse monoclonal antibody, clone 10C12
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400150) , 20ug Explanation
100ul 325 In Stock
CF500334
  • Carrier-free (BSA/glycerol-free) L1CAM mouse monoclonal antibody, clone 10C12
100ug $450 3-4 weeks
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(2)
IHC(4)
FC(1)
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Also for L1CAM (NM_000425)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human L1CAM (NP_000416) produced in HEK293T cell.
Clone Nameclone 10C12 IsotypeIgG1
Species ReactivityHuman Concentration0.26 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:500~1000, IHC 1:50, FLOW 1:100
Predicted MW Explanation 140.0 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens L1 cell adhesion molecule (L1CAM), transcript variant 1
Alternative NameCAML1; CD171; HSAS; HSAS1; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1
Database LinkNP_000416
Entrez Gene 3897 Human
FunctionThe protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Axon guidanceCell adhesion molecules (CAMs)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY L1CAM (RC211601, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-L1CAM.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-L1CAM monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-L1CAM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500334)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-L1CAM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500334)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Ovary tissue using anti-L1CAM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500334)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-L1CAM mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500334)
FC Image
HEK293T cells transfected with either RC211601 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-L1CAM antibody(TA500334), and then analyzed by flow cytometry.

 

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