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Home Antibody All anti-Klra3 antibodies

Anti-Klra3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306712
  • Rabbit Polyclonal KLRA3 Antibody
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenKLRA3 antibody was raised against a 14 amino acid peptide near the carboxy terminus of mouse KLRA3.
Clone Name IsotypeIgG
Species ReactivityMouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 2 - 4 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameMus musculus killer cell lectin-like receptor, subfamily A, member 3 (Klra3), transcript variant 1
Alternative Name5E6; Ly49c; Nk-2; NK-2.1; Nk2; Nk2.1
Database LinkNP_034778
FunctionKLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide –receptive H-2Kb. This antibody may cross-react with other LY49 receptors.
Related Pathway

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WB Image
Western blot analysis of KLRA3 in mouse brain tissue lysate with KLRA3 antibody at 2 µg/ml.

 

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