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Home Antibody All anti-Kcnip2 antibodies

Anti-Kcnip2 Antibody S60-73

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326563
  • Mouse Monoclonal Anti-KChiP2 Antibody
100µg 325 3-7 Days
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WB(1)
IHC(1)
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Also for Kcnip2 (NM_001033961)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenFusion protein amino acids 1-252 (Full length) of rat KChIP2b
Clone NameS60-73 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1mg/mL
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
BufferPBS pH7.4, 50% glycerol
Purification Protein G Purified
Note Detects ~35kDa. No cross-reactivity against rat KCHiPs 1, 3

Reference Data

Target NameRattus norvegicus Kv channel-interacting protein 2 (Kcnip2), transcript variant c
Alternative NameKchip2
Database LinkNP_001029133
FunctionThere are four member of the KChiPs (Kv4 potassium channel interacting protein) family. They are all EF handcontaining proteins required for the traffic of channelforming Kv4 K+ subunits to the plasma membrane . KChiP2 expression has been found to be significantly decreased in hypertrophy and heart failure , and does so thru modulatin of intracellular concentration and calcineurin/NFAT pathways . It has also been found that KChiP2 also functionally modulates the Cav1.2 goverened Ltype calcium channel through a direct interaction between KChiP2 and the amino-terminus of Cav1.2 .
Related Pathway

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WB Image
Western blot analysis on rat brain membrane tissues using a 1:1000 dilution of the antibody
IHC Image
IHC analysis of KChIP2 in frozen sections of mouse brain extract using the antibody

 

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