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Home Antibody All anti-Kcnip2 antibodies

Anti-Kcnip2 Antibody S60-73

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326563
  • Mouse Monoclonal Anti-KChiP2 Antibody
100µg 325 3-7 Days
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WB(1)
IHC(1)
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Also for Kcnip2 (NM_001033961)
cDNA Clone shRNA/siRNA Primer Pair Protein Request Antibody

OriGene Data

ImmunogenFusion protein amino acids 1-252 (Full length) of rat KChIP2b
Clone NameS60-73 IsotypeIgG1
Species ReactivityHuman, Mouse, Rat Concentration1mg/mL
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
BufferPBS pH7.4, 50% glycerol
Purification Protein G Purified
Note Detects ~35kDa. No cross-reactivity against rat KCHiPs 1, 3

Reference Data

Target NameRattus norvegicus Kv channel-interacting protein 2 (Kcnip2), transcript variant c
Alternative NameKchip2
Database LinkNP_001029133
Entrez Gene 30819 Human
Entrez Gene 80906 Mouse
Entrez Gene 56817 Rat
FunctionThere are four member of the KChiPs (Kv4 potassium channel interacting protein) family. They are all EF handcontaining proteins required for the traffic of channelforming Kv4 K+ subunits to the plasma membrane . KChiP2 expression has been found to be significantly decreased in hypertrophy and heart failure , and does so thru modulatin of intracellular concentration and calcineurin/NFAT pathways . It has also been found that KChiP2 also functionally modulates the Cav1.2 goverened Ltype calcium channel through a direct interaction between KChiP2 and the amino-terminus of Cav1.2 .
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis on rat brain membrane tissues using a 1:1000 dilution of the antibody
IHC Image
IHC analysis of KChIP2 in frozen sections of mouse brain extract using the antibody

 

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