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Anti-Kcnb1 Antibody S4-11
Also for Kcnb1 (NM_013186)
|Bacterially expressed GST Bacterially expressed GSTfusion protein corresponding to amino acids 509-853 of rat KV2.1, |
|Human, Mouse, Rat, Monkey
||WB: 1ug/ml, IHC: 0.1-1ug/ml, IF: 1-10ug/ml
|PBS pH7.4, 50% glycerol|
|Protein G Purified
|Detects ~105-125kDa. Recognizes the Shab related a- subunit Kv2.1.
|Rattus norvegicus potassium voltage gated channel, Shab-related subfamily, member 1 (Kcnb1)|
|DRK1PC; Kcr1-1; Kv2.1; Shab|
|Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alphasubunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1- KV4 subfamilies generate functional K+ channels in a homotetrameric configuration. The KV2 subfamily consists of KV2.1 and KV2.2, and both have very similar properties. Members of the KV2 subfamily are widely expressed in neuronal tissues. They have also been reported in neurons in the dorsal root ganglia .|
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IHC analysis of Kv2.1 tested on mouse brain hippocampus showing strong membrane staining of neurons, using a dilution of the antibody