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Home Antibody All anti-KSR1 antibodies

Anti-KSR1 Antibody EPR2421Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310648
  • Rabbit Monoclonal antibody against KSR1
100ul 325 In Stock
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human KSR1 is used as an immunogen..
Clone NameEPR2421Y IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:10,000 - 100,000; IHC 1:500-1,000; ICC: 1: 100 - 250; IP: 1:40; FC: 1:60;
BufferStore at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens kinase suppressor of ras 1 (KSR1)
Alternative NameKSR; RSU2
Database LinkNP_055053
Entrez Gene 8844 Human
Entrez Gene 16706 Mouse
FunctionKinase suppressor of Ras (KSR) is a conserved component of the Ras pathway that interacts directly with MEK and MAPK. It has been shown that KSR1 translocates from the cytoplasm to the cell surface in response to growth factor treatment and that this process is regulated by MARK3 (1). MARK3 seems to be a positive regulator of the beta-catenin pathway and an inhibitor of the JNK pathway. These findings show that MARK3, a regulator of polarity, is also a modulator of Wnt-beta-catenin signaling, indicating a link between two important developmental pathways (2.
Related PathwayProtein KinaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Anti-KSR1 antibody [EPR2421Y] (TA310648) at 1/2000 dilution + 293 cell lysate at 10 ug. Secondary: HRP goat anti-rabbit at 1/2000 dilution

 

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