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 Home All anti-KRT8 antibodies

Anti-KRT8 Phospho Antibody EP1630

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SKU Description Amount Price Availability*  
TA307459
  • Rabbit monoclonal antibody against Cytokeratin 8 Phospho (pS431) (clone EP1630 ) (Phospho-Specific)
100ul $325 3-7 Days
TA802519S
  • Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9
 30ul
$100
$50*		 In Stock
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* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
WB(1)
IHC(1)
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Also for KRT8 (NM_002273)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues surrounding Serine 431 of human Cytokeratin 8 was used as an immunogen. The antibody only detects Cytokeratin 8 phosphorylated at Serine 431.
Clone NameEP1630 IsotypeRabbit IgG
Species ReactivityHuman Concentration
Guaranteed Application *WB, IHC Suggested DilutionsICC: 1:100 - 250, IHC: 1:100 - 250, IP: 1:50, WB: 1:10,000 - 50,000,
BufferStore at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Reference Data

Target NameHomo sapiens keratin 8 (KRT8), transcript variant 2
Alternative NameCARD2; CK-8; CK8; CYK8; K2C8; K8; KO
Database LinkNP_002264
FunctionKeratin polypeptides 8 and 18 (K8/18) are intermediate filament phosphoglycoproteins that are expressed preferentially in glandular epithelia. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells (1-3). Together with actin microfilaments and microtubules, keratin filaments make up the cytoskeletons of vertebrate epithelial cells, forming alpha-helical coiled-coil dimers which associate laterally and end-to-end to form 10-nm diameter filaments (4).
Related Pathway
EGFR1 Signaling Pathway

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WB Image
A.Western blot analysis on HeLa lysates using anti-Phospho-Cytokeratin 8 (pS431) RabMAb .
IHC Image
C. Immunohistochemical analysis of paraffin-embedded human stomach adenocarcinoma using anti-Phospho-Cytokeratin 8 RabMAb .

 

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